The film serves as a conclusion to the story of the MCU up to that point, ending the story arcs for several main characters. The Russo brothers joined as directors in April 2015, with Markus and McFeely signing on to write the script a month later. The film was announced in October 2014 as Avengers: Infinity War – Part 2, but Marvel later removed this title. In the film, the surviving members of the Avengers and their allies attempt to reverse Thanos's actions in Infinity War. Directed by Anthony and Joe Russo and written by Christopher Markus and Stephen McFeely, the film features an ensemble cast including Robert Downey Jr., Chris Evans, Mark Ruffalo, Chris Hemsworth, Scarlett Johansson, Jeremy Renner, Don Cheadle, Paul Rudd, Brie Larson, Karen Gillan, Danai Gurira, Benedict Wong, Jon Favreau, Bradley Cooper, Gwyneth Paltrow, and Josh Brolin. Produced by Marvel Studios and distributed by Walt Disney Studios Motion Pictures, it is the direct sequel to Avengers: Infinity War (2018) and the 22nd film in the Marvel Cinematic Universe (MCU).

Many consider Infinity War and Endgame to be the MCU's peak, so it's difficult to imagine the Multiverse Saga's only Avengers films living up to their success.Avengers: Endgame is a 2019 American superhero film based on the Marvel Comics superhero team the Avengers.

While these promise to be massive additions to the MCU, there is an expectation that The Kang Dynasty and Secret Wars will match the impact of Infinity War and Endgame, but this is a monumental task. Though not much has been revealed about the storylines that will unfold in The Kang Dynasty and Secret Wars, it's thought that Earth's Mightiest Heroes will be pitted against the villainous Kang the Conqueror and his variants while also dealing with the threat of a multiversal incursion. At SDCC 2022, Marvel Studios chief Kevin Feige detailed plans to replicate this with Phase 6's Avengers films concluding the Multiverse Saga, but they have a huge, and potentially impossible, task on their hands. Ten years of MCU projects in the Infinity Saga culminated in 2018's Avengers: Infinity War and 2019's Avengers: Endgame, which brought all the franchise's heroes together in an effort to thwart the Mad Titan Thanos' destructive plans. Bringing the MCU's Multiverse Saga to a close, Avengers: The Kang Dynasty and Avengers: Secret Wars will surely struggle to match the success of Marvel Studios' epic crossover double-feature Infinity War and Endgame.

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